Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Propionic Acid SCHEMBL28551997 | 0.90 | FFAR1 (0.56) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL19438684 | 0.84 | PLAAT3 (0.51) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL901671 | 0.84 | CYP4F2 (0.55) | KMT2APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7060197 | 0.84 | PLAAT3 (0.58) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL7716761 | 0.83 | SIRT2 (0.51) | ALDH1A1SIRT2 | |
| SCHEMBL378633 | 0.83 | SLC7A5 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28312879 | 0.82 | L3MBTL1 (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| Methyl 3-Phenylpropanoate SCHEMBL28101617 | 0.82 | PARP1 (0.56) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL1623264 | 0.81 | TAAR1 (0.47) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9542924 | 0.81 | TAAR1 (0.55) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197036-B | Method for performing anti-mahalanobis hydrogen carboxylation reaction on photocatalytic olefin compound and carbon dioxide | 中国科学院理化技术研究所 | 2024-01-23 | — | — | CN | disclosed |
| CN-115197036-A | Method for carrying out anti-Ma hydrocarboxylation reaction on olefin compound and carbon dioxide by photocatalysis | 中国科学院理化技术研究所 | 2022-10-18 | — | — | CN | disclosed |
| EP-3504197-B1 | NEW TRIFLUOROMETHYLPROPANAMIDE DERIVATIVES AS HTRA1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3484859-B1 | NEW DIFLUOROKETAMIDE DERIVATIVES AS HTRA1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-09-15 | — | — | EP | disclosed |
| EP-2970215-B1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBVIE DEUTSCHLAND (DE) | 2019-04-17 | — | — | EP | disclosed |
| WO-2018036957-A1 | NEW TRIFLUOROMETHYLPROPANAMIDE DERIVATIVES AS HTRA1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-03-01 | — | — | WO | disclosed |
| WO-2018036942-A1 | NEW DIFLUOROKETAMIDE DERIVATIVES AS HTRA1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-03-01 | — | — | WO | disclosed |
| US-9656955-B2 | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBVIE INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-9650334-B2 | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBVIE INC. (US) | 2017-05-16 | — | — | US | disclosed |
| EP-2970215-A1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-01-20 | — | — | EP | disclosed |
| EP-2027132-B1 | THIAZOLO-PYRAMIDINE / PYRIDINE UREA DERIVATIVES AS ADENOSINE A2B RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-09-15 | — | — | EP | disclosed |
| WO-2007134958-A1 | THIAZOLO-PYRAMIDINE / PYRIDINE UREA DERIVATIVES AS ADENOSINE A2B RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270433-A1 | Thiazolo-pyrimidine/pyridine urea derivatives | BRINKMAN JOHN A | 2007-11-22 | — | — | US | disclosed |
| US-5260277-A | Cell receptor antagonists | TANABE SEIYAKU CO., LTD. (JP) | 1993-11-09 | — | — | US | disclosed |
| WO-1993008823-A1 | GUANIDINYL AND RELATED CELL ADHESION MODULATION COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 1993-05-13 | — | — | WO | disclosed |
| US-4138577-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138575-A | 11-Deoxy-16-phenoxy-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138576-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138573-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4126754-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270433-A1 | Thiazolo-pyrimidine/pyridine urea derivatives | ADORA2B, UTS2R, TBXA2R | KMT2A 3413/4885MEN1 4682/4885PLAAT3 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.