Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392039 | 0.80 | ADORA2B (0.47) | KMT2AL3MBTL1CYP3A4HPGDMTNR1A | |
| SCHEMBL8394257 | 0.80 | ADORA2B (0.47) | KMT2AL3MBTL1CYP3A4HPGDMTNR1A | |
| SCHEMBL10159514 | 0.80 | MAPT (0.49) | KMT2AL3MBTL1CYP3A4HPGDMTNR1A | |
| SCHEMBL4771735 | 0.80 | BCHE (0.56) | KMT2AL3MBTL1HPGDMAPTTSHR | |
| SCHEMBL1031237 | 0.79 | HPGD (0.73) | KMT2AL3MBTL1CYP3A4HPGDMAPT | |
| SCHEMBL4760053 | 0.78 | CYP3A4 (0.71) | KMT2ACYP3A4HPGDMAPTMEN1 | |
| SCHEMBL10159519 | 0.76 | TSHR (0.45) | KMT2AL3MBTL1CYP3A4HPGDMAPT | |
| SCHEMBL6446786 | 0.76 | CYP3A4 (0.68) | KMT2AL3MBTL1CYP3A4HPGDMAPT | |
| SCHEMBL3979221 | 0.76 | HPGD (0.68) | KMT2AL3MBTL1CYP3A4HPGDMAPT | |
| SCHEMBL3619264 | 0.76 | MCHR1 (0.39) | KMT2AL3MBTL1CYP3A4HPGDMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510545-A2 | 1,3 substituted 6-aminouraciles to stabilize halogenated polymers | Wehner, Wolfgang, Dr. (DE) | 2005-03-02 | — | — | EP | disclosed |
| EP-0967245-A1 | 1,3 substituted 6-aminouraciles to stabilize halogenated polymers | Witco Vinyl Additives GmbH (DE) | 1999-12-29 | — | — | EP | disclosed |