Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979221 | 0.94 | HPGD (0.68) | CYP3A4HPGDALDH1A1BCHEACHE | |
| SCHEMBL4760053 | 0.92 | CYP3A4 (0.71) | CYP3A4HPGDALDH1A1ADORA3C5AR1 | |
| SCHEMBL1031237 | 0.85 | HPGD (0.73) | CYP3A4HPGDALDH1A1C5AR1L3MBTL1 | |
| SCHEMBL2336285 | 0.83 | ALDH1A1 (0.45) | CYP3A4HPGDALDH1A1ADRA2AL3MBTL1 | |
| SCHEMBL10561004 | 0.83 | HPGD (0.49) | CYP3A4HPGDALDH1A1BCHEACHE | |
| SCHEMBL29142975 | 0.81 | CYP3A4 (1.00) | CYP3A4HPGDALDH1A1ADORA3C5AR1 | |
| SCHEMBL1948066 | 0.81 | ADORA2B (0.46) | CYP3A4HPGDALDH1A1ADRA2AL3MBTL1 | |
| SCHEMBL29738657 | 0.79 | ADRA2A (0.45) | CYP3A4HPGDALDH1A1ADRA2A | |
| SCHEMBL3977468 | 0.78 | SMN1; SMN2 (0.48) | CYP3A4HPGDALDH1A1ADORA3L3MBTL1 | |
| SCHEMBL1030465 | 0.77 | CYP3A4 (0.59) | CYP3A4HPGDALDH1A1C5AR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510545-A2 | 1,3 substituted 6-aminouraciles to stabilize halogenated polymers | Wehner, Wolfgang, Dr. (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-6274654-B1 | 1,3-Disubstituted 6-aminouracils for stabilizing halogenated polymers | WITCO VINYL ADDITIVES GMBH (DE) | 2001-08-14 | — | — | US | disclosed |
| EP-0967245-A1 | 1,3 substituted 6-aminouraciles to stabilize halogenated polymers | Witco Vinyl Additives GmbH (DE) | 1999-12-29 | — | — | EP | disclosed |