SCHEMBL1031237

SCHEMBL1031237

Nc1cc(=O)n(Cc2ccccc2)c(=O)n1Cc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.73
CYP3A4 P08684 2/20 0.73
ALDH1A1 P00352 3/20 0.58
C5AR1 P21730 1/20 0.49
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GSK3A P49840 2/20 0.47
GSK3B P49841 2/20 0.47
F2 P00734 1/20 0.47
PLG P00747 1/20 0.47
ELANE P08246 1/20 0.47
CTSG P08311 1/20 0.47
CMA1 P23946 1/20 0.47
CTRC Q99895 1/20 0.47
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
KDM4A O75164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4760053 0.88 CYP3A4 (0.71) HPGDCYP3A4ALDH1A1C5AR1KMT2A
SCHEMBL3979221 0.85 HPGD (0.68) HPGDCYP3A4ALDH1A1C5AR1KMT2A
SCHEMBL6446786 0.85 CYP3A4 (0.68) HPGDCYP3A4ALDH1A1C5AR1KMT2A
SCHEMBL29142975 0.85 CYP3A4 (1.00) HPGDCYP3A4ALDH1A1C5AR1KMT2A
SCHEMBL8830850 0.83 HPGD (0.66) HPGDCYP3A4ALDH1A1KMT2AMEN1
SCHEMBL25383417 0.83 KMT2A (0.54) HPGDCYP3A4ALDH1A1KMT2AMEN1
SCHEMBL1030465 0.82 CYP3A4 (0.59) HPGDCYP3A4ALDH1A1C5AR1KMT2A
SCHEMBL8985073 0.80 GSK3B (0.67) HPGDCYP3A4ALDH1A1C5AR1KMT2A
SCHEMBL25827018 0.80 HPGD (0.57) HPGDCYP3A4ALDH1A1C5AR1KMT2A
SCHEMBL30951218 0.80 CYP3A4 (0.61) HPGDCYP3A4ALDH1A1C5AR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107501807-B A kind of cold lamination film having highly resistance Ultraviolet Oxidation performance and anti-microbial property 浙江越千树数码科技有限公司 2019-08-27 CN claimed
CN-107501807-A It is a kind of to possess high uvioresistant oxidation susceptibility and the cold lamination film of anti-microbial property 浙江越千树数码科技有限公司 2017-12-22 CN claimed
CN-107501807-B A kind of cold lamination film having highly resistance Ultraviolet Oxidation performance and anti-microbial property 浙江越千树数码科技有限公司 2019-08-27 CN disclosed
EP-2792707-B1 Stabiliser systems for polymers containing halogens IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO KG (DE) 2018-06-06 EP disclosed
CN-107501807-A It is a kind of to possess high uvioresistant oxidation susceptibility and the cold lamination film of anti-microbial property 浙江越千树数码科技有限公司 2017-12-22 CN disclosed
US-9834520-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-12-05 US disclosed
EP-2392612-B1 FLAME-PROOF POLYMERS CONTAINING HALOGEN WITH IMPROVED THERMOSTABILITY HUBER CORP J M (US) 2017-01-11 EP disclosed
US-20160229814-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-08-11 US disclosed
EP-2975031-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-01-20 EP disclosed
EP-2110405-B1 STABILISER SYSTEMS FOR POLYMERS CONTAINING HALOGEN IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO KG (DE) 2015-09-02 EP disclosed
EP-2792707-A2 Stabiliser systems for polymers containing halogens IKA Innovative Kunststoffaufbereitung Gmbh & Co.Kg (DE) 2014-10-22 EP disclosed
EP-2110405-A1 Stabiliser systems for polymers containing halogen IKA Innovative Kunststoffaufbereitung Gmbh & Co.Kg (DE) 2009-10-21 EP disclosed
US-20090131564-A1 COORDINATION-POLYMERIC TRIETHANOLAMINEPERCHLORATO(TRIFLATO)METAL INNER COMPLEXES AS ADDITIVES FOR SYNTHETIC POLYMERS IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2009-05-21 US disclosed
US-20090105387-A1 Coordination-polymeric triethanolamineperchlorato(triflato)metal inner complexes as additives for synthetic polymers ARTEMIS RESEARCH GMBH & CO. KG (DE) 2009-04-23 US disclosed
WO-2009021652-A1 STABILIZER SYSTEM FOR HALOGENATED POLYMERS NABALTEC AG (DE) 2009-02-19 WO disclosed
EP-1771507-A2 STABILISER SYSTEM FOR HALOGENATED POLYMERS Artemis Research GmbH & Co.KG (DE) 2007-04-11 EP disclosed
WO-2006013040-A2 STABILISER SYSTEM FOR HALOGENATED POLYMERS ARTEMIS RESEARCH GMBH & CO. KG (DE) 2006-02-09 WO disclosed
EP-1510545-A2 1,3 substituted 6-aminouraciles to stabilize halogenated polymers Wehner, Wolfgang, Dr. (DE) 2005-03-02 EP disclosed
US-6274654-B1 1,3-Disubstituted 6-aminouracils for stabilizing halogenated polymers WITCO VINYL ADDITIVES GMBH (DE) 2001-08-14 US disclosed
EP-0967245-A1 1,3 substituted 6-aminouraciles to stabilize halogenated polymers Witco Vinyl Additives GmbH (DE) 1999-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160229814-A1 HETEROCYCLIC COMPOUND RORB, RORC, RORA HPGD 1281/4885CYP3A4 326/4885ALDH1A1 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.