Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762876 | 0.89 | EPHX2 (0.61) | ALDH1A1GAASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL5338240 | 0.87 | POLB (0.67) | ALDH1A1GAASMN1; SMN2KMT2ATDP1 | |
| SCHEMBL12010889 | 0.84 | ALDH1A1 (0.78) | ALDH1A1GAASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL12793391 | 0.83 | GAA (0.79) | ALDH1A1GAASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL6450019 | 0.81 | CYP2C9 (0.60) | ALDH1A1SMN1; SMN2EPHX2KMT2AL3MBTL1 | |
| SCHEMBL4001115 | 0.80 | EPHX2 (1.00) | GAAEPHX2KMT2AL3MBTL1MEN1 | |
| SCHEMBL1140815 | 0.79 | KMT2A (0.69) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12490995 | 0.79 | L3MBTL1 (0.74) | ALDH1A1GAASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL4075002 | 0.79 | L3MBTL1 (1.00) | ALDH1A1GAASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL8692256 | 0.76 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568696-A1 | Compounds as inhibitors of cell proliferation and viral infections | 4SC AG (DE) | 2005-08-31 | — | — | EP | disclosed |