SCHEMBL6450175

SCHEMBL6450175

COc1cc[c]c(C2CC2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.38
DRD2 P14416 2/20 0.34
DRD3 P35462 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
FDFT1 P37268 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ACHE P22303 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945046 0.93 PTGDR2 (0.38) HTR2CDRD2CHRNB4CHRNA3ALDH1A1
SCHEMBL9597736 0.91 PTGDR2 (0.40) HTR2CALDH1A1
SCHEMBL2887323 0.82 HTR2C (0.48) HTR2CMEN1KMT2A
SCHEMBL8835486 0.80 NQO1 (0.39) ALDH1A1MEN1KMT2A
SCHEMBL28826417 0.77 CHRNB2 (0.35) ALDH1A1KMT2A
SCHEMBL28072594 0.77 TRPV1 (0.36) DRD2DRD3SLC6A2SLC6A4SLC6A3
SCHEMBL9093780 0.77 LTA4H (0.41) SLC6A2SLC6A4SLC6A3
SCHEMBL28874105 0.74 CYP1A2 (0.34) CA12CA1CA2CA7CA9
SCHEMBL457257 0.74 HTR2C (0.32) HTR2C
SCHEMBL16955735 0.71 CA1 (0.39) HTR2CDRD2DRD3CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103368-A EIF4E inhibitors and uses thereof 皮克医疗公司 2024-05-28 CN disclosed
US-10986839-B2 Substituted oxadiazoles for combating phytopathogenic fungi BASF SE (DE) 2021-04-27 US disclosed
US-20190159454-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2019-05-30 US disclosed
EP-3442951-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2019-02-20 EP disclosed
WO-2017178245-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2017-10-19 WO disclosed
CN-106573931-A Bet-protein inhibiting 3,4-dihydropyrido[2,3-b]pyrazinones with meta-substituted aromatic amino- or ether groups 拜耳医药股份有限公司 2017-04-19 CN disclosed
US-6964974-B2 2,3-oxidosqualene-lanosterol cyclase inhibitors HOFFMANN-LA ROCHE INC. (US) 2005-11-15 US disclosed
CN-1553900-A Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents ��ʱ��ʩ����ҩ��˾ 2004-12-08 CN disclosed
EP-0835242-A1 THIOAMIDES S-OXIDES FOR USE AS PESTICIDES Novartis AG (CH) 1998-04-15 EP disclosed
WO-1997000859-A1 THIOAMIDES S-OXIDES FOR USE AS PESTICIDES NOVARTIS AG (CH) 1997-01-09 WO disclosed
US-5563168-A FUNGICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-10-08 US disclosed
US-5387607-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1995-02-07 US disclosed
US-5292759-A O-benzyloxime ethers and crop protection agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1994-03-08 US disclosed
US-5194662-A Insecticides, fungicides for plants BASF AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190159454-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI CYP51A1, ERG28, DPM1 HTR2C 3996/4885DRD2 1535/4885DRD3 975/4885
US-10986839-B2 Substituted oxadiazoles for combating phytopathogenic fungi CYP51A1, ERG28, DPM1 HTR2C 3996/4885DRD2 1535/4885DRD3 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.