SCHEMBL8835486

SCHEMBL8835486

CCOc1cc[c]c(C2CC2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.39
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
KMT2A Q03164 2/20 0.34
NPC1 O15118 2/20 0.34
MEN1 O00255 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
HPGD P15428 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ABL1 P00519 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
ESR2 Q92731 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8941628 0.87 GAA (0.35) NQO1KMT2ANPC1MEN1HPGD
SCHEMBL6450175 0.80 HTR2C (0.38) KMT2AMEN1ALDH1A1
SCHEMBL15352665 0.75 NQO1 (0.38) NQO1TP53CYP3A4KMT2ANPC1
SCHEMBL10945046 0.74 PTGDR2 (0.38) KMT2ANPC1MEN1RAB9ASMN1; SMN2
SCHEMBL16957518 0.74 NQO1 (0.45) NQO1KMT2ANPC1MEN1HPGD
SCHEMBL15067112 0.74 NQO1 (0.48) NQO1TP53CYP3A4KMT2ANPC1
SCHEMBL15063639 0.73 TRPA1 (0.32) SMN1; SMN2
SCHEMBL9093780 0.72 LTA4H (0.41) NPC1RAB9AHSD17B10TSHR
SCHEMBL9597736 0.72 PTGDR2 (0.40) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL28826417 0.72 CHRNB2 (0.35) CHRNB2CHRNA4KMT2AALDH1A1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5633268-A FUNGICIDES, INSECTICIDES, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed
US-5563168-A FUNGICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-10-08 US disclosed
US-5194662-A Insecticides, fungicides for plants BASF AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed