SCHEMBL6451245

SCHEMBL6451245

OC1c2ccccc2N=NN1O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 4/20 0.33
NOS3 P29474 2/20 0.33
NOS2 P35228 2/20 0.33
BCHE P06276 2/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7491186 0.78 NOS3 (0.33) NOS1NOS3NOS2
SCHEMBL27640459 0.74 NOS3 (0.31) NOS1NOS3NOS2
SCHEMBL17555026 0.68 MAOA (0.33)
SCHEMBL13633898 0.65 NOS1 (0.36) NOS1NOS3NOS2
SCHEMBL941406 0.65 NOS1 (0.39) NOS1NOS3NOS2
Water SCHEMBL6608061 0.64 MAOA (0.32)
SCHEMBL27561460 0.60 NOS1 (0.37) NOS1NOS3NOS2
SCHEMBL17120918 0.57
SCHEMBL11298936 0.57 EDNRA (0.42)
SCHEMBL14028182 0.57 EDNRA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6903199-B2 Crosslinked amide derivatives of hyaluronic acid and manufacturing method thereof LG LIFE SCIENCES LTD. (KR) 2005-06-07 US claimed
EP-0164070-B1 SALTS OF 3-HYDROXY-4-OXO-3,4-DIHYDRO-1,2,3-BENZOTRIAZINE AND AMINO COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-19 EP claimed
US-9327050-B2 Hemostatic material containing nano-fiber containing synthetic collagen JNC CORPORATION (JP) 2016-05-03 US disclosed
US-20130251780-A1 HEMOSTATIC MATERIAL CONTAINING NANO-FIBER CONTAINING SYNTHETIC COLLAGEN JNC CORPORATION (JP) 2013-09-26 US disclosed
EP-0072352-A1 Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use CIBA-GEIGY AG (CH) 1983-02-16 EP disclosed