SCHEMBL27640459

SCHEMBL27640459

O=CC1c2ccccc2N=NN1O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6451245 0.74 NOS1 (0.33) NOS3NOS1NOS2
SCHEMBL27813729 0.73 NOS3 (0.36) NOS3NOS1NOS2
SCHEMBL27683902 0.72
SCHEMBL28953288 0.67 SIGMAR1 (0.36)
SCHEMBL7491186 0.66 NOS3 (0.33) NOS3NOS1NOS2
SCHEMBL27701767 0.66 LMNA (0.32) NOS3NOS1NOS2
SCHEMBL27777917 0.65 CACNA1G (0.44) NOS3NOS1NOS2
SCHEMBL27271568 0.65 CACNA1G (0.39) NOS3NOS1NOS2
SCHEMBL28417169 0.64 NOS3 (0.33) NOS3NOS1NOS2
SCHEMBL28844025 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110862357-B Benzotriazine compound and synthesis method and application thereof 浙江工业大学 2021-06-08 CN claimed
CN-110862357-A Benzotriazine compound and synthesis method and application thereof 浙江工业大学 2020-03-06 CN claimed
CN-115975295-B High-strength high-toughness modified polypropylene nano injection molding material and preparation method thereof 大韩高性能材料(广东)有限公司 2023-08-15 CN disclosed
CN-115975295-A High-strength high-toughness modified polypropylene nano injection molding material and preparation method thereof 大韩高性能材料(广东)有限公司 2023-04-18 CN disclosed
CN-110862357-B Benzotriazine compound and synthesis method and application thereof 浙江工业大学 2021-06-08 CN disclosed
CN-110862357-B Benzotriazine compound and synthesis method and application thereof 浙江工业大学 2021-06-08 CN disclosed
CN-110862357-A Benzotriazine compound and synthesis method and application thereof 浙江工业大学 2020-03-06 CN disclosed
CN-110862357-A Benzotriazine compound and synthesis method and application thereof 浙江工业大学 2020-03-06 CN disclosed
CN-110590901-A Method for quickly constructing trace peptide library and synthesis device thereof 浙江昂拓莱司生物技术有限公司 2019-12-20 CN disclosed
CN-1758910-A Use of isoquinoline derivatives for treating cancer and MAP kinase related diseases NOVARTIS AG (CH) 2006-04-12 CN disclosed