Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.89 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.67 |
| ▸ | CYP2C8 | P10632 | 5/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.67 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.67 |
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.59 |
| ▸ | IAPP | P10997 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.58 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrocurcumin SCHEMBL29372158 | 0.94 | ALOX5 (1.00) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| Tetrahydrocurcumin SCHEMBL284877 | 0.94 | ALOX5 (1.00) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| Tetrahydrocurcumin SCHEMBL29370299 | 0.94 | ALOX5 (1.00) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL12775013 | 0.93 | ALOX5 (0.80) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL10307817 | 0.90 | ALOX5 (0.91) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL10307533 | 0.90 | ALOX5 (0.91) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| Tetrahydrodemethoxycurcumin SCHEMBL29565582 | 0.89 | ALOX5 (0.89) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| Tetrahydrodemethoxycurcumin SCHEMBL4413210 | 0.89 | ALOX5 (0.89) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL10307751 | 0.89 | ALOX5 (0.89) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL28355932 | 0.88 | ALOX5 (0.88) | ALOX5OR51E2CYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1901618-B1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO KG (DE) | 2009-06-17 | — | — | EP | claimed |
| US-20080227866-A1 | Hydroxyphenylalkadiones and Their Use for Masking Bitter Taste and/or for Intensifying Sweet Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-18 | — | — | US | claimed |
| EP-1901618-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | Symrise GmbH & Co. KG (DE) | 2008-03-26 | — | — | EP | claimed |
| WO-2007003527-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-01-11 | — | — | WO | claimed |
| CN-116178125-A | Tetrahydrocurcumin derivative and preparation method and application thereof | 南方医科大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-110261496-B | Method for detecting content of tetrahydrocurcumin | 四川省中医药科学院 | 2022-04-05 | — | — | CN | disclosed |
| US-8119696-B2 | Treatment of superficial and cutaneous mycoses with a pure form of 1,7-bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione | Majeed, Muhammed (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090275665-A1 | Enhanced biological potential of greater than 99% pure form of 1, 7-bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione over corresponding 95% pure form-therapeutic and agricultural applications thereof | SAMI LABS LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
| EP-1901618-B1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO KG (DE) | 2009-06-17 | — | — | EP | disclosed |
| EP-1901618-B1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO KG (DE) | 2009-06-17 | — | — | EP | disclosed |
| US-20080227866-A1 | Hydroxyphenylalkadiones and Their Use for Masking Bitter Taste and/or for Intensifying Sweet Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080227866-A1 | Hydroxyphenylalkadiones and Their Use for Masking Bitter Taste and/or for Intensifying Sweet Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080227866-A1 | Hydroxyphenylalkadiones and Their Use for Masking Bitter Taste and/or for Intensifying Sweet Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-18 | — | — | US | disclosed |
| WO-2008042755-A2 | INHIBITORS OF COGNITIVE DECLINE | COGNITION THERAPEUTICS, INC. (US) | 2008-04-10 | — | — | WO | disclosed |
| EP-1901618-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | Symrise GmbH & Co. KG (DE) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007003527-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007003527-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275665-A1 | Enhanced biological potential of greater than 99% pure form of 1, 7-bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione over corresponding 95% pure form-therapeutic and agricultural applications thereof | CYP8B1, HPD, HAAO | ALOX5 268/4885OR51E2 906/4885CYP3A4 94/4885 |
| US-20080227866-A1 | Hydroxyphenylalkadiones and Their Use for Masking Bitter Taste and/or for Intensifying Sweet Taste | TAS2R1, TAS2R5, TAS2R50 | ALOX5 1881/4885OR51E2 30/4885CYP3A4 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.