Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 7/20 | 0.58 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | L1CAM | P32004 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542670 | 0.89 | KDM4E (0.54) | KDM4EHTTTLR7ALDH1A1NPC1 | |
| SCHEMBL1147702 | 0.86 | KDM4E (0.73) | KDM4EHTTTLR7ALDH1A1NPC1 | |
| SCHEMBL6450640 | 0.82 | KDM4E (0.60) | KDM4EHTTTLR7ALDH1A1NPC1 | |
| SCHEMBL6449069 | 0.82 | RAB9A (0.62) | KDM4EHTTTLR7ALDH1A1NPC1 | |
| SCHEMBL77381 | 0.82 | CA1 (0.77) | KDM4EHTTALDH1A1L1CAMCA1 | |
| SCHEMBL12894824 | 0.80 | KDM4E (0.54) | KDM4EHTTTLR7ALDH1A1NPC1 | |
| SCHEMBL6449695 | 0.79 | RAB9A (0.66) | KDM4EHTTTLR7ALDH1A1NPC1 | |
| SCHEMBL14810907 | 0.79 | KDM4E (0.67) | KDM4EHTTTLR7ALDH1A1NPC1 | |
| SCHEMBL30118935 | 0.79 | KMT2A (0.58) | KDM4EHTTALDH1A1CA1CA9 | |
| SCHEMBL8710005 | 0.79 | KMT2A (0.58) | KDM4EHTTALDH1A1CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | KDM4E 3106/4885HTT 1540/4885TLR7 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.