SCHEMBL6452238

SCHEMBL6452238

CCCCC[C@H]1CC[C@@H]2CC(c3ccc(C(=O)Oc4ccc(C#N)c(F)c4)cc3)CC[C@H]2C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP2C9 P11712 2/20 0.34
HPGD P15428 1/20 0.34
MAPT P10636 3/20 0.33
LMNA P02545 3/20 0.33
TRPC3 Q13507 1/20 0.33
TRPC6 Q9Y210 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
PRSS1 P07477 1/20 0.33
ACR P10323 1/20 0.33
NPC1 O15118 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6452243 1.00 RAB9A (0.35) RAB9AALDH1A1CYP2C9HPGDMAPT
SCHEMBL6461071 0.99 ALDH1A1 (0.35) RAB9AALDH1A1CYP2C9HPGDMAPT
SCHEMBL6451358 0.99 ALDH1A1 (0.35) RAB9AALDH1A1CYP2C9HPGDMAPT
SCHEMBL6461066 0.99 ALDH1A1 (0.35) RAB9AALDH1A1CYP2C9HPGDMAPT
SCHEMBL6451361 0.99 ALDH1A1 (0.35) RAB9AALDH1A1CYP2C9HPGDMAPT
SCHEMBL6452071 0.97 RAB9A (0.35) RAB9AALDH1A1CYP2C9HPGDMAPT
SCHEMBL6452073 0.97 RAB9A (0.35) RAB9AALDH1A1CYP2C9HPGDMAPT
SCHEMBL6460714 0.94 CYP2C9 (0.40) RAB9AALDH1A1CYP2C9MAPTLMNA
SCHEMBL6460711 0.94 CYP2C9 (0.40) RAB9AALDH1A1CYP2C9MAPTLMNA
SCHEMBL7514450 0.91 CYP2C9 (0.42) RAB9AALDH1A1CYP2C9HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed