Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461066 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HPGDRAB9APRSS1ACR | |
| SCHEMBL6451361 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HPGDRAB9APRSS1ACR | |
| SCHEMBL6451358 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HPGDRAB9APRSS1ACR | |
| SCHEMBL6452243 | 0.99 | RAB9A (0.35) | ALDH1A1HPGDRAB9APRSS1ACR | |
| SCHEMBL6452238 | 0.99 | RAB9A (0.35) | ALDH1A1HPGDRAB9APRSS1ACR | |
| SCHEMBL6452073 | 0.97 | RAB9A (0.35) | ALDH1A1HPGDRAB9APRSS1ACR | |
| SCHEMBL6452071 | 0.97 | RAB9A (0.35) | ALDH1A1HPGDRAB9APRSS1ACR | |
| SCHEMBL6460714 | 0.93 | CYP2C9 (0.40) | ALDH1A1RAB9ACYP2C9TRPC3TRPC6 | |
| SCHEMBL6460711 | 0.93 | CYP2C9 (0.40) | ALDH1A1RAB9ACYP2C9TRPC3TRPC6 | |
| SCHEMBL13325809 | 0.90 | CYP2C9 (0.42) | ALDH1A1HPGDRAB9APRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |