Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460711 | 1.00 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6452071 | 0.95 | RAB9A (0.35) | CYP2C9ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6452073 | 0.95 | RAB9A (0.35) | CYP2C9ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6452243 | 0.94 | RAB9A (0.35) | CYP2C9ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6452238 | 0.94 | RAB9A (0.35) | CYP2C9ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6461071 | 0.93 | ALDH1A1 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6451358 | 0.93 | ALDH1A1 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6461066 | 0.93 | ALDH1A1 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6451361 | 0.93 | ALDH1A1 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6452687 | 0.93 | TRPV4 (0.35) | CYP2C9ALDH1A1LMNAMAPTTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |