Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.32 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452645 | 1.00 | SIGMAR1 (0.35) | SIGMAR1DGAT1SOAT1HTR2CTEAD1 | |
| SCHEMBL6457327 | 0.91 | ALDH1A1 (0.34) | SIGMAR1DGAT1SOAT1HTR2CTEAD1 | |
| SCHEMBL6457320 | 0.91 | ALDH1A1 (0.34) | SIGMAR1DGAT1SOAT1HTR2CTEAD1 | |
| SCHEMBL6453216 | 0.89 | SIGMAR1 (0.33) | SIGMAR1DGAT1SOAT1HTR2CTEAD1 | |
| SCHEMBL6453207 | 0.89 | SIGMAR1 (0.33) | SIGMAR1DGAT1SOAT1HTR2CTEAD1 | |
| SCHEMBL6457872 | 0.88 | GAA (0.34) | SIGMAR1DGAT1SOAT1HTR2CTEAD1 | |
| SCHEMBL6457875 | 0.88 | GAA (0.34) | SIGMAR1DGAT1SOAT1HTR2CTEAD1 | |
| SCHEMBL6458285 | 0.88 | PTGS2 (0.35) | — | |
| SCHEMBL6458284 | 0.88 | PTGS2 (0.35) | — | |
| SCHEMBL6461154 | 0.87 | GAA (0.36) | SIGMAR1P2RY14GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |