SCHEMBL645265

SCHEMBL645265

Cc1ccc(OC(=O)CCC(=O)Oc2ccc(C)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.69
LMNA P02545 3/20 0.69
ALDH1A1 P00352 3/20 0.69
MAPT P10636 1/20 0.69
HTT P42858 1/20 0.69
HSD17B10 Q99714 1/20 0.69
MEN1 O00255 1/20 0.59
GAA P10253 2/20 0.59
L3MBTL1 Q9Y468 3/20 0.52
TDP1 Q9NUW8 2/20 0.51
NPC1 O15118 1/20 0.51
BCL9 O00512 1/20 0.49
CTNNB1 P35222 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21185916 0.94 KMT2A (0.62) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL11577260 0.94 KMT2A (0.62) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL11579236 0.92 KMT2A (0.60) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL13854911 0.92 LMNA (0.72) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL23843934 0.92 KMT2A (0.60) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL206680 0.91 KMT2A (0.62) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL5696793 0.91 KMT2A (0.62) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL11579725 0.90 KMT2A (0.58) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL32670860 0.90 KMT2A (0.81) KMT2ALMNAALDH1A1MAPTHTT
SCHEMBL20563199 0.90 KMT2A (0.60) KMT2ALMNAALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN claimed
EP-3625284-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
EP-3625283-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
US-11548980-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2023-01-10 US disclosed
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN disclosed
EP-2723750-B1 DIKETOPYRROLOPYRROLE OLIGOMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES CLAP CO LTD (KR) 2022-08-10 EP disclosed
US-11306179-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2022-04-19 US disclosed
US-20210403640-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-12-30 US disclosed
US-20210139645-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-05-13 US disclosed
EP-2751855-B1 DIKETOPYRROLOPYRROLE OLIGOMERS AND COMPOSITIONS, COMPRISING DIKETOPYRROLOPYRROLE OLIGOMERS BASF SE (DE) 2020-10-28 EP disclosed
US-6566519-B2 Reacting succinic diester with nitrile CLARIANT INTERNATIONAL LTD. (CH) 2003-05-20 US disclosed
WO-2003022847-A2 PROCESS FOR THE DIRECT PREPARATION OF PYRROLO[3,4-C]PYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-03-20 WO disclosed
WO-2003022848-A2 PROCESS FOR THE PREPARATION OF DIKETOPYRROLOPYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-03-20 WO disclosed
EP-0962499-B1 Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles CIBA SC HOLDING AG (CH) 2003-03-05 EP disclosed
US-6361594-B1 ONE-STEP PROCESS USING CRYSTAL GROWTH INHIBITORS DURING SYNTHESIS; NO SIZE REDUCTION NEEDED; HIGH DISPERSABILITY, TINCTORIAL STRENGTH, PURITY, AND MIGRATION, HEAT, LIGHT AND WEATHERING FASTNESS CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-26 US disclosed
US-20020010331-A1 Reacting succinic diester with nitrile CLARIANT GMBH 2002-01-24 US disclosed
US-6057449-A HEATING A DISUCCINATE WITH A NITRILE IN THE PRESENCE OF BASE CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
EP-0962499-A2 Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles Ciba SC Holding AG (CH) 1999-12-08 EP disclosed
US-5492564-A HIGH OPACITY, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1996-02-20 US disclosed
US-4579949-A REACTING DISUCCINATE WITH NITRILES CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010331-A1 Reacting succinic diester with nitrile SDHA, QDPR, SDHB KMT2A 2122/4885LMNA 4110/4885ALDH1A1 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.