Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959111 | 0.86 | CTSD (0.47) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL26444538 | 0.86 | GAA (0.50) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL31424918 | 0.86 | SMN1; SMN2 (0.48) | CA1CA9ALDH1A1MAPTNPC1 | |
| SCHEMBL2486733 | 0.84 | L3MBTL1 (0.48) | CA1CA9ALDH1A1MAPTNPC1 | |
| SCHEMBL7042282 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL962276 | 0.81 | ALDH1A1 (0.62) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL335962 | 0.81 | MAPT (0.45) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL30638320 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL20621120 | 0.81 | MEN1 (0.51) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL10708923 | 0.81 | TP53 (0.41) | ALDH1A1MAPTNPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |
| CN-103261300-B | Comprise hydrazides, hydrazone and polyamines based on natural rubber and the compositions of white carbon black | 米其林集团总公司 | 2016-08-10 | — | — | CN | disclosed |
| EP-2248833-B1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | BRIDGESTONE CORP (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-20130289165-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-10-31 | — | — | US | disclosed |
| EP-2655495-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | Compagnie Générale des Etablissements Michelin (FR) | 2013-10-30 | — | — | EP | disclosed |
| CN-103261300-A | Composition based on natural rubber and carbon black comprising hydrazide, hydrazone and polyamine | MICHELIN RECH TECH | 2013-08-21 | — | — | CN | disclosed |
| US-8389641-B2 | Modified diene rubber, production method thereof, and rubber composition and tire using the rubber | BRIDGESTONE CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| WO-2012084821-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2012-06-28 | — | — | WO | disclosed |
| US-20110003911-A1 | MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2248833-A1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | Bridgestone Corporation (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100249336-A1 | MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER | BRIDGESTONE CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| CN-101842393-A | Modified natural rubber, process for producing the same, rubber composition and tire using the same | BRIDGESTONE CORP | 2010-09-22 | — | — | CN | disclosed |
| EP-2206730-A1 | MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME | Bridgestone Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |