Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453314 | 1.00 | DRD1 (0.38) | DRD1IDO1LMNAMAT2AALDH1A1 | |
| SCHEMBL14228593 | 0.96 | LMNA (0.39) | IDO1LMNAMAT2AALDH1A1ESR2 | |
| SCHEMBL6456893 | 0.86 | FASN (0.37) | IDO1LMNAMAT2AALDH1A1 | |
| SCHEMBL6456899 | 0.86 | FASN (0.37) | IDO1LMNAMAT2AALDH1A1 | |
| SCHEMBL9061934 | 0.86 | ESR2 (0.47) | DRD1IDO1LMNAMAT2AALDH1A1 | |
| SCHEMBL9061943 | 0.86 | ESR2 (0.47) | DRD1IDO1LMNAMAT2AALDH1A1 | |
| SCHEMBL6458937 | 0.85 | MAT2A (0.35) | DRD1LMNAMAT2AALDH1A1 | |
| SCHEMBL6458931 | 0.85 | MAT2A (0.35) | DRD1LMNAMAT2AALDH1A1 | |
| SCHEMBL6460483 | 0.84 | SLC6A2 (0.38) | IDO1LMNAMAT2AALDH1A1 | |
| SCHEMBL6460474 | 0.84 | SLC6A2 (0.38) | IDO1LMNAMAT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |