Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 11/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458931 | 1.00 | MAT2A (0.35) | MAT2ALMNAALDH1A1CHRNB2CHRNA7 | |
| SCHEMBL6459535 | 0.87 | MEN1 (0.33) | MAT2ACHRNB2CHRNA4 | |
| SCHEMBL6459540 | 0.87 | MEN1 (0.33) | MAT2ACHRNB2CHRNA4 | |
| SCHEMBL6456893 | 0.86 | FASN (0.37) | MAT2ALMNAALDH1A1 | |
| SCHEMBL6456899 | 0.86 | FASN (0.37) | MAT2ALMNAALDH1A1 | |
| SCHEMBL6460316 | 0.86 | GRM2 (0.34) | — | |
| SCHEMBL6460319 | 0.86 | GRM2 (0.34) | — | |
| SCHEMBL6454487 | 0.85 | MAT2A (0.34) | MAT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL6454491 | 0.85 | MAT2A (0.34) | MAT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL6453310 | 0.85 | DRD1 (0.38) | MAT2ALMNAALDH1A1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |