Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | CTSG | P08311 | 4/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.41 |
| ▸ | CMA1 | P23946 | 4/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813059 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PRSS1 | |
| SCHEMBL8813051 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PRSS1 | |
| SCHEMBL9382586 | 0.83 | SMN1; SMN2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PRSS1 | |
| SCHEMBL642839 | 0.83 | SMN1; SMN2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PRSS1 | |
| SCHEMBL8364820 | 0.82 | MT-CO2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL4648001 | 0.82 | MT-CO2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL2276227 | 0.82 | MT-CO2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL1208677 | 0.82 | SMN1; SMN2 (0.37) | PRSS1CTSGCTRB1CMA1KMT2A | |
| SCHEMBL6832851 | 0.82 | USP30 (0.32) | PRSS1CTSGCTRB1CMA1MMP13 | |
| SCHEMBL5846260 | 0.82 | KMT2A (0.40) | KMT2AMEN1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237897-B1 | ANTITHROMBOTIC COMPOUND | MERCK SHARP & DOHME (NL) | 2015-01-14 | — | — | EP | disclosed |
| US-6875755-B2 | Antithrombotic compound | AKZO NOBEL N.V. (NL) | 2005-04-05 | — | — | US | disclosed |
| US-20030114361-A1 | Antithrombotic compound | MERCK SHARP & DOHME B.V. (NL) | 2003-06-19 | — | — | US | disclosed |
| EP-1237897-A2 | ANTITHROMBOTIC COMPOUND | Akzo Nobel N.V. (NL) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042262-A2 | ANTITHROMBOTIC COMPOUND | AKZO NOBEL N.V. (NL) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114361-A1 | Antithrombotic compound | SERPINC1, ADAMTS13, F2 | CHRNB2 4761/4885CHRNB4 4712/4885CHRNA3 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.