Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5557107 | 0.88 | NPSR1 (0.43) | ALDH1A1MAPTNPSR1TSHRHPGD | |
| SCHEMBL5564443 | 0.88 | NPSR1 (0.46) | ALDH1A1MAPTNPSR1TSHRHPGD | |
| SCHEMBL6455153 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTNPSR1TSHRHPGD | |
| SCHEMBL5561977 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTNPSR1TSHRHPGD | |
| SCHEMBL5559856 | 0.81 | NPSR1 (0.40) | ALDH1A1MAPTNPSR1TSHRHPGD | |
| SCHEMBL5565995 | 0.80 | KDM4E (0.48) | ALDH1A1MAPTNPSR1TSHRHPGD | |
| SCHEMBL5560541 | 0.80 | SENP1 (0.43) | ALDH1A1MAPTNPSR1L3MBTL1HSD17B1 | |
| SCHEMBL5560390 | 0.80 | MAPKAPK2 (0.42) | ALDH1A1MAPTL3MBTL1LMNATDP1 | |
| SCHEMBL5565065 | 0.78 | NPSR1 (0.42) | MAPTNPSR1TSHRHPGDMAPK1 | |
| SCHEMBL1588116 | 0.77 | HPGD (0.51) | ALDH1A1MAPTNPSR1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575933-A1 | ENANTIOMERS OF THIOPHENE HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HDAC INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004054999-A1 | ENANTIOMERS OF THIOPHENE HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HDAC INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-01 | — | — | WO | disclosed |