Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917953 | 1.00 | MAOA (0.34) | MAOAMAOBS1PR1S1PR4S1PR5 | |
| SCHEMBL6463945 | 1.00 | MAOA (0.34) | MAOAMAOBS1PR1S1PR4S1PR5 | |
| SCHEMBL6463943 | 1.00 | MAOA (0.34) | MAOAMAOBS1PR1S1PR4S1PR5 | |
| SCHEMBL6456196 | 0.99 | MAOA (0.32) | MAOAMAOBS1PR1S1PR4S1PR5 | |
| SCHEMBL6456188 | 0.99 | MAOA (0.32) | MAOAMAOBS1PR1S1PR4S1PR5 | |
| SCHEMBL6455927 | 0.96 | NAAA (0.32) | MAOAMAOBRAB9ASCN9AALDH1A1 | |
| SCHEMBL6455934 | 0.96 | NAAA (0.32) | MAOAMAOBRAB9ASCN9AALDH1A1 | |
| SCHEMBL6456985 | 0.93 | ALDH1A1 (0.36) | SCN9AALDH1A1LMNAMAPT | |
| SCHEMBL6456980 | 0.93 | ALDH1A1 (0.36) | SCN9AALDH1A1LMNAMAPT | |
| SCHEMBL6453950 | 0.89 | MAOA (0.36) | MAOAMAOBS1PR1S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |