Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456980 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTCYP2C9SCN9A | |
| SCHEMBL6455927 | 0.94 | NAAA (0.32) | ALDH1A1LMNAMAPTCYP2C9SCN9A | |
| SCHEMBL6455934 | 0.94 | NAAA (0.32) | ALDH1A1LMNAMAPTCYP2C9SCN9A | |
| SCHEMBL6456196 | 0.94 | MAOA (0.32) | ALDH1A1LMNAMAPTSCN9ANR1H4 | |
| SCHEMBL6456188 | 0.94 | MAOA (0.32) | ALDH1A1LMNAMAPTSCN9ANR1H4 | |
| SCHEMBL6455982 | 0.93 | MAOA (0.34) | ALDH1A1LMNAMAPTSCN9A | |
| SCHEMBL6463945 | 0.93 | MAOA (0.34) | ALDH1A1LMNAMAPTSCN9A | |
| SCHEMBL6463943 | 0.93 | MAOA (0.34) | ALDH1A1LMNAMAPTSCN9A | |
| SCHEMBL7917953 | 0.93 | MAOA (0.34) | ALDH1A1LMNAMAPTSCN9A | |
| SCHEMBL6452532 | 0.92 | SCN9A (0.33) | SCN9ASLC6A3SLC6A4NR1H4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |