SCHEMBL4884781

SCHEMBL4884781

Cc1cc(C=O)c(C)n1-c1cccnc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.63
ALDH1A1 P00352 11/20 0.62
MAPT P10636 6/20 0.62
KDM4E B2RXH2 4/20 0.62
HPGD P15428 4/20 0.62
BLM P54132 1/20 0.62
PKM P14618 1/20 0.62
RAB9A P51151 6/20 0.59
SMN1; SMN2 Q16637 6/20 0.59
MEN1 O00255 3/20 0.59
POLB P06746 2/20 0.59
RECQL P46063 1/20 0.59
NPC1 O15118 4/20 0.58
TCF4 P15884 1/20 0.57
CTNNB1 P35222 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
APEX1 P27695 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645648 0.80 POLB (0.68) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL21225209 0.78 ALDH1A1 (0.55) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL16218479 0.77 KMT2A (0.60) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL14315202 0.77 ALDH1A1 (1.00) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL12222500 0.76 POLB (0.67) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL16218484 0.75 KMT2A (0.61) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL14325640 0.75 RAB9A (0.68) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL16221729 0.75 ALDH1A1 (1.00) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL28802526 0.75 ALOX12 (0.43) KMT2AALDH1A1MAPTKDM4EHPGD
SCHEMBL29728425 0.75 ALOX12 (0.43) KMT2AALDH1A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114878727-A Method for determining hymexazol residues in tobacco 合肥高尔生命健康科学研究院有限公司 2022-08-09 CN claimed
CN-114878727-B Method for determining hymexazol residues in tobacco 合肥高尔生命健康科学研究院有限公司 2023-07-25 CN disclosed
CN-114878727-A Method for determining hymexazol residues in tobacco 合肥高尔生命健康科学研究院有限公司 2022-08-09 CN disclosed
WO-2019152731-A1 ANDROGEN RECEPTOR ANTAGONISTS ALPINE ANDROSCIENCES, INC. (US) 2019-08-08 WO disclosed
US-20080281105-A1 Novel Quinolinium Salts and Derivatives IMMUSOL INCORPORATED (US) 2008-11-13 US disclosed
CN-101106992-A Novel quinolinium salts and derivatives IMMUSOL INC (US) 2008-01-16 CN disclosed
EP-1841428-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES Immusol Incorporated (US) 2007-10-10 EP disclosed
WO-2006078754-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES IMMUSOL INCORPORATED (US) 2006-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281105-A1 Novel Quinolinium Salts and Derivatives NQO2, MCL1, KRAS KMT2A 944/4885ALDH1A1 3206/4885MAPT 2491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.