Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 9/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457265 | 1.00 | GAA (0.35) | GAAMAPTCNR2DRD2LSS | |
| SCHEMBL6457258 | 1.00 | GAA (0.35) | GAAMAPTCNR2DRD2LSS | |
| SCHEMBL6456711 | 1.00 | GAA (0.35) | GAAMAPTCNR2DRD2LSS | |
| SCHEMBL6452592 | 0.99 | DRD2 (0.35) | GAAMAPTCNR2DRD2LSS | |
| SCHEMBL6452587 | 0.99 | DRD2 (0.35) | GAAMAPTCNR2DRD2LSS | |
| SCHEMBL6456957 | 0.96 | DRD2 (0.36) | GAAMAPTCNR2DRD2IDO1 | |
| SCHEMBL6456961 | 0.96 | DRD2 (0.36) | GAAMAPTCNR2DRD2IDO1 | |
| SCHEMBL6460854 | 0.91 | ALDH1A1 (0.38) | MAPTDRD2IDO1SLC6A2SLC6A4 | |
| SCHEMBL6460852 | 0.91 | ALDH1A1 (0.38) | MAPTDRD2IDO1SLC6A2SLC6A4 | |
| SCHEMBL11134951 | 0.90 | DRD2 (0.41) | GAAMAPTDRD2LSSIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |