Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460854 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTCYP2C9DRD2 | |
| SCHEMBL6456957 | 0.93 | DRD2 (0.36) | ALDH1A1LMNAMAPTCYP2C9DRD2 | |
| SCHEMBL6456961 | 0.93 | DRD2 (0.36) | ALDH1A1LMNAMAPTCYP2C9DRD2 | |
| SCHEMBL6452587 | 0.92 | DRD2 (0.35) | MAPTDRD2IDO1SLC6A4SLC6A2 | |
| SCHEMBL6452592 | 0.92 | DRD2 (0.35) | MAPTDRD2IDO1SLC6A4SLC6A2 | |
| SCHEMBL6456711 | 0.91 | GAA (0.35) | MAPTDRD2IDO1SLC6A4SLC6A2 | |
| SCHEMBL6457258 | 0.91 | GAA (0.35) | MAPTDRD2IDO1SLC6A4SLC6A2 | |
| SCHEMBL6456705 | 0.91 | GAA (0.35) | MAPTDRD2IDO1SLC6A4SLC6A2 | |
| SCHEMBL6457265 | 0.91 | GAA (0.35) | MAPTDRD2IDO1SLC6A4SLC6A2 | |
| SCHEMBL7920178 | 0.90 | SLC6A4 (0.38) | DRD2IDO1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |