Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456961 | 1.00 | DRD2 (0.36) | DRD2IDO1CNR2SLC6A4SLC6A2 | |
| SCHEMBL6452587 | 0.97 | DRD2 (0.35) | DRD2IDO1CNR2SLC6A4SLC6A2 | |
| SCHEMBL6452592 | 0.97 | DRD2 (0.35) | DRD2IDO1CNR2SLC6A4SLC6A2 | |
| SCHEMBL6456705 | 0.96 | GAA (0.35) | DRD2IDO1CNR2SLC6A4SLC6A2 | |
| SCHEMBL6457265 | 0.96 | GAA (0.35) | DRD2IDO1CNR2SLC6A4SLC6A2 | |
| SCHEMBL6456711 | 0.96 | GAA (0.35) | DRD2IDO1CNR2SLC6A4SLC6A2 | |
| SCHEMBL6457258 | 0.96 | GAA (0.35) | DRD2IDO1CNR2SLC6A4SLC6A2 | |
| SCHEMBL6460854 | 0.93 | ALDH1A1 (0.38) | DRD2IDO1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6460852 | 0.93 | ALDH1A1 (0.38) | DRD2IDO1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11139778 | 0.89 | DRD2 (0.43) | DRD2IDO1SLC6A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |