Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095285 | 0.87 | KMT2A (0.52) | ALDH1A1HIF1AKMT2ASMN1; SMN2ESR1 | |
| SCHEMBL11655934 | 0.87 | HIF1A (0.66) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| SCHEMBL28665285 | 0.87 | KMT2A (0.60) | ALDH1A1HIF1AKMT2ASMN1; SMN2ESR1 | |
| SCHEMBL6691158 | 0.84 | HSD17B10 (0.52) | HIF1AMAPK1KMT2ASMN1; SMN2ESR1 | |
| SCHEMBL17479830 | 0.82 | GSK3B (0.53) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| SCHEMBL10831193 | 0.82 | ELANE (0.56) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| Clofenoxyde SCHEMBL882741 | 0.81 | GSK3B (0.61) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| SCHEMBL11480265 | 0.80 | GSK3B (0.80) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| SCHEMBL4643847 | 0.79 | CA1 (0.58) | ALDH1A1KMT2AMAPTPOLBRAB9A | |
| SCHEMBL10768902 | 0.79 | KMT2A (0.49) | GSK3BALDH1A1HIF1AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250944-A1 | Synthesis and uses of synephrine derivatives | SYNTECH (SSPF) INTERNATIONAL INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250944-A1 | Synthesis and uses of synephrine derivatives | ADRB3, ADRB2, ADRB1 | GSK3B 191/4885ALDH1A1 3209/4885HIF1A 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.