Clofenoxyde

Clofenoxyde

SCHEMBL882741

O=C(CCl)c1ccc(Oc2ccc(C(=O)CCl)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.61
ALDH1A1 P00352 6/20 0.58
HIF1A Q16665 2/20 0.58
TRPA1 O75762 1/20 0.58
MAPK1 P28482 1/20 0.58
PARP10 Q53GL7 4/20 0.52
HPGD P15428 3/20 0.52
MAPT P10636 3/20 0.52
RAB9A P51151 2/20 0.52
PARP15 Q460N3 2/20 0.52
KMT2A Q03164 1/20 0.52
PARP14 Q460N5 1/20 0.52
PARP16 Q8N5Y8 1/20 0.52
PARP11 Q9NR21 1/20 0.52
PARP4 Q9UKK3 1/20 0.52
ERCC5 P28715 1/20 0.52
FEN1 P39748 1/20 0.52
MMP1 P03956 2/20 0.50
TP53 P04637 1/20 0.50
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1593331 0.92 GSK3B (0.67) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL15756687 0.92 GSK3B (0.77) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL883109 0.86 TNKS (0.58) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL11480265 0.85 GSK3B (0.80) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL2314649 0.83 HDAC3 (0.66) GSK3BALDH1A1MAPK1PARP10HPGD
SCHEMBL10886176 0.83 GSK3B (0.57) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL18355732 0.82 MAPT (0.55) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL14555314 0.82 THRB (0.72) ALDH1A1HPGDMAPTRAB9APOLB
SCHEMBL6458347 0.81 GSK3B (0.55) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL10886125 0.81 L3MBTL1 (0.56) GSK3BALDH1A1HIF1ATRPA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-0177490-A4 (VINYLARYL)ALKYL POLYSULFIDE POLYMERS. DOW CHEMICAL CO (US) 1986-09-04 EP claimed
US-4608433-A ELASTOMER PLASTICIZERS THE DOW CHEMICAL COMPANY (US) 1986-08-26 US claimed
EP-0177490-A1 (VINYLARYL)ALKYL POLYSULFIDE POLYMERS THE DOW CHEMICAL COMPANY (US) 1986-04-16 EP claimed
WO-1985004177-A1 (VINYLARYL)ALKYL POLYSULFIDE POLYMERS THE DOW CHEMICAL COMPANY (US) 1985-09-26 WO claimed
US-4438259-A PROTECTIVE COATINGS, SEALS, CAULKING, ADHESIVES THE DOW CHEMICAL COMPANY (US) 1984-03-20 US claimed
WO-2025088587-A1 COMPOSITIONS COMPRISING ENHANCED MULTISPECIFIC BINDING AGENTS FOR AN IMMUNE RESPONSE JANSSEN BIOTECH, INC. (US) 2025-05-01 WO disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
EP-0177490-A1 (VINYLARYL)ALKYL POLYSULFIDE POLYMERS THE DOW CHEMICAL COMPANY (US) 1986-04-16 EP disclosed
WO-1985004177-A1 (VINYLARYL)ALKYL POLYSULFIDE POLYMERS THE DOW CHEMICAL COMPANY (US) 1985-09-26 WO disclosed
US-4438259-A PROTECTIVE COATINGS, SEALS, CAULKING, ADHESIVES THE DOW CHEMICAL COMPANY (US) 1984-03-20 US disclosed
US-4069341-A OXYBIS(4,1-PHENYLENE(2-OXO-2,1-ETHANEDIYL)) THIOCYANATE AND ITS USE AS AN ANTIMICROBIAL AGENT THE DOW CHEMICAL COMPANY (US) 1978-01-17 US disclosed
US-3957832-A EPOXY RESINS PREPARED FROM POLYHYDROXY-CONTAINING COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1976-05-18 US disclosed