Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465162 | 0.69 | CEL (0.35) | CEL | |
| Hydrochloric Acid SCHEMBL6553929 | 0.69 | PTGS2 (0.31) | — | |
| SCHEMBL6459763 | 0.67 | CEL (0.33) | CEL | |
| Hydrochloric Acid SCHEMBL6465548 | 0.66 | MEN1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL2777881 | 0.65 | — | — | |
| SCHEMBL239469 | 0.62 | ABCB1 (0.43) | CEL | |
| Hydrochloric Acid SCHEMBL6453947 | 0.61 | — | — | |
| SCHEMBL9439521 | 0.61 | CEL (0.33) | CEL | |
| SCHEMBL14353365 | 0.61 | ABCB1 (0.42) | CEL | |
| SCHEMBL27524766 | 0.60 | CEL (0.38) | CEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049704-B1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | BASELL POLYOLEFINE GMBH (DE) | 2005-07-27 | — | — | EP | disclosed |
| US-6433203-B1 | COORDINATION POLYMERIZATION CATALYST; ALPHA-OLEFIN POLYMER | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-08-13 | — | — | US | disclosed |
| EP-1049704-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | Montell Technology Company bv (NL) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000031088-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-06-02 | — | — | WO | disclosed |