Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6554723 | 0.73 | HTR2C (0.33) | HTR1AHTR7 | |
| SCHEMBL28063342 | 0.71 | CYP11B2 (0.34) | PTGS2HTR1AHTR7 | |
| SCHEMBL7598197 | 0.69 | PTGDR2 (0.35) | PTGS2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6459144 | 0.69 | CEL (0.30) | — | |
| Hydrochloric Acid SCHEMBL6553477 | 0.69 | KDM4E (0.31) | HTR1AHTR7 | |
| SCHEMBL31240954 | 0.64 | HTR2C (0.52) | PTGS2HTR1AHTR7 | |
| SCHEMBL42781 | 0.62 | PTGDR2 (0.48) | PTGS2 | |
| Hydrochloric Acid SCHEMBL6465548 | 0.62 | MEN1 (0.35) | — | |
| SCHEMBL239469 | 0.61 | ABCB1 (0.43) | PTGS2HTR1AHTR7 | |
| Benzene SCHEMBL27853973 | 0.61 | PTGDR2 (0.52) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773237-B1 | Olefin polymerization catalyst system | MITSUI CHEMICALS INC (JP) | 2004-02-18 | — | — | EP | disclosed |