SCHEMBL645917

SCHEMBL645917

CC(C#N)CCCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 4/20 0.50
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MMP12 P39900 2/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP13 P45452 1/20 0.41
MMP14 P50281 1/20 0.41
KCNH2 Q12809 1/20 0.40
HSD11B1 P28845 1/20 0.40
HDAC2 Q92769 1/20 0.40
FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931777 0.90 SIGMAR1 (0.43)
SCHEMBL7754777 0.83 FAAH (0.49)
SCHEMBL3764837 0.82 FDFT1 (0.49) FDFT1TSHRHSD17B10MMP12MMP2
SCHEMBL8939338 0.81 TSHR (0.50) FDFT1TSHRHSD17B10HSD11B1
SCHEMBL8939310 0.81 FDFT1 (0.48) FDFT1TSHRHSD17B10HSD11B1
SCHEMBL27492664 0.80 FDFT1 (0.57) FDFT1MMP12MMP2MMP9MMP13
SCHEMBL8939339 0.80 TSHR (0.53) FDFT1TSHRHSD17B10HSD11B1
SCHEMBL10322372 0.79 CTSK (0.47) TSHR
SCHEMBL8939328 0.78 TSHR (0.55) FDFT1TSHRHSD17B10HSD11B1
SCHEMBL8939308 0.78 TSHR (0.55) FDFT1TSHRHSD17B10HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031713-B Diarylethene-based multiple image storage material, and preparation and application thereof 华中科技大学 2022-08-30 CN claimed
CN-110527523-B Dual-image storage material, preparation method and application thereof 华中科技大学 2020-09-08 CN claimed
US-8574688-B2 Blue phase liquid crystal composition SONY CORPORATION (JP) 2013-11-05 US claimed
US-6849321-B2 Surfaces with gradients in surface topography WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2005-02-01 US claimed
US-20020142453-A1 Optical amplification of molecular interactions using liquid crystals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-10-03 US claimed
US-5498363-A Electrorheological fluid AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-03-12 US claimed
WO-2023060368-A1 MICROFLUIDIC CHIP CAPABLE OF FINELY ADJUSTING COAXIAL ARRANGEMENT OF CAPILLARY TUBES 北京永康乐业科技发展有限公司 2023-04-20 WO disclosed
CN-115712211-A Method for enhancing nanosecond electro-optic response in positive liquid crystal under isotropic phase 南京邮电大学 2023-02-24 CN disclosed
CN-111247405-B Polarization camera device 国立大学法人长冈技术科学大学 2022-10-18 CN disclosed
CN-114031713-B Diarylethene-based multiple image storage material, and preparation and application thereof 华中科技大学 2022-08-30 CN disclosed
CN-114031713-A Diarylethene-based multiple image storage material, and preparation and application thereof 华中科技大学 2022-02-11 CN disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 US disclosed
US-10788715-B2 Photo-alignment material and photo-alignment method TOKYO INSTITUTE OF TECHNOLOGY (JP) 2020-09-29 US disclosed
EP-1022324-A2 Liquid crystal composite material and liquid crystal display device(s) which use them SEIKO EPSON CORPORATION (JP) 2000-07-26 EP disclosed
US-5972240-A LIQUID CRYSTAL COMPOSITE MATERIALS CONTAINING ORGANIC COMPOUNDS ENABLE THE LOWERING OF THE DRIVE VOLTAGE OF LIQUID CRYSTAL DISPLAY DEVICES AND OF LIQUID CRYSTAL DISPLAY DEVICES OF A POLYMER-DISPERSION TYPE SEIKO EPSON CORPORATION (JP) 1999-10-26 US disclosed
WO-1999032878-A1 LIQUID CRYSTAL SENSORS NICHOLAS PAUL (GB) 1999-07-01 WO disclosed
EP-0730019-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT PRODUCED THEREFROM SEIKO EPSON CORPORATION (JP) 1996-09-04 EP disclosed
US-5498363-A Electrorheological fluid AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-03-12 US disclosed
US-5498363-A Electrorheological fluid AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-03-12 US disclosed
US-5368770-A Method of preparing thin liquid crystal films KENT STATE UNIVERSITY (US) 1994-11-29 US disclosed