Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29695950 | 1.00 | BRD4 (0.34) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL7200620 | 0.90 | BRD4 (0.31) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL27670339 | 0.88 | DRD2 (0.39) | KIF11PARP1 | |
| Hydrochloric Acid SCHEMBL27464017 | 0.88 | BRD4 (0.30) | BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL14812511 | 0.86 | NPC1 (0.33) | BRD4CREBBPKIF11 | |
| Hydrochloric Acid SCHEMBL28753283 | 0.86 | KCNH2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL27442413 | 0.85 | EDNRB (0.38) | — | |
| Hydrochloric Acid SCHEMBL7084089 | 0.85 | SYK (0.33) | — | |
| Hydrochloric Acid SCHEMBL5604826 | 0.85 | BRD4 (0.33) | BRD4 | |
| Hydrochloric Acid SCHEMBL7170563 | 0.84 | BRD4 (0.32) | BRD4CREBBPKIF11PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599661-B | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2024-03-12 | — | — | CN | disclosed |
| CN-110167973-B | High purity polypropylene for molding and polypropylene composition | 道达尔研究技术弗吕公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114599661-A | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2022-06-07 | — | — | CN | disclosed |
| EP-1534724-A2 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2005-06-01 | — | — | EP | disclosed |
| US-6794019-B2 | MOLDING MATERIALS; USING COORDINATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2004-09-21 | — | — | US | disclosed |
| WO-2004020479-A2 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-03-11 | — | — | WO | disclosed |
| US-20030236378-A1 | For producing propylene polymers that are suited for fiber spinning | BASELL POLYOLEFINE GMBH (DE) | 2003-12-25 | — | — | US | disclosed |