Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 7/20 | 0.40 |
| ▸ | NOS2 | P35228 | 7/20 | 0.40 |
| ▸ | NOS3 | P29474 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819459 | 0.76 | PNMT (0.48) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL5037735 | 0.76 | PNMT (0.48) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL4342311 | 0.75 | PNMT (0.40) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL1452550 | 0.73 | TAAR1 (0.34) | ALDH1A1CYP3A4SLC6A2TAAR1MAOA | |
| SCHEMBL1680442 | 0.72 | PNMT (0.48) | PNMTENPP2LOXL2NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL921011 | 0.71 | NOS1 (0.49) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL36008 | 0.70 | LOXL2 (0.71) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL10422276 | 0.70 | LOXL2 (0.71) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL22170131 | 0.69 | PNMT (0.45) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL84035 | 0.68 | PNMT (0.48) | PNMTENPP2LOXL2NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562640-A2 | METHODS FOR PURIFYING RADIOLABELLED COMPOUNDS | Molecular Insight Pharmaceuticals, Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004035744-A2 | METHODS FOR PURIFYING RADIOLABELLED COMPOUNDS | BIOSTREAM, INC. (US) | 2004-04-29 | — | — | WO | disclosed |