Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.48 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS2 | P35228 | 4/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3353456 | 0.98 | PNMT (0.47) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL23861649 | 0.89 | PNMT (0.40) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL12831490 | 0.87 | PNMT (0.48) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL28856242 | 0.85 | PNMT (0.47) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL29607349 | 0.83 | ENPP2 (0.50) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL27986627 | 0.83 | ENPP2 (0.50) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL8988941 | 0.83 | ENPP2 (0.50) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL18798726 | 0.83 | TAAR1 (0.57) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL3841734 | 0.83 | TAAR1 (0.57) | LOXL2NOS1KIF11ALDH1A1SMN1; SMN2 | |
| SCHEMBL27298195 | 0.83 | PNMT (0.45) | PNMTENPP2LOXL2NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153561-B1 | 9H-FLUOREN DERIVATES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | UNIV JAGIELLONSKI (PL) | 2026-04-29 | — | — | EP | disclosed |
| US-12492163-B2 | 9H-fluorene derivatives or their pharmaceutically acceptable salts | UNIWERSYTET JAGIELLONSKI (PL) | 2025-12-09 | — | — | US | disclosed |
| CN-119970993-A | Traditional Chinese medicine oral gargle for tissue repair and preparation method thereof | 广东乐草元健康产业有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4393937-A1 | STEROID COMPOUND AND CONJUGATE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| US-20240206470-A1 | VOLATILE APPLICATIONS AGAINST PATHOGENS | AGROFRESH INC (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240068009-A1 | SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES | PROMEGA CORPORATION | 2024-02-29 | — | — | US | disclosed |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-01-11 | — | — | US | disclosed |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2023227698-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| US-20050101590-A1 | Cannabinoid receptor agonists | SHIONOGI & CO., LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
| WO-2005035535-A1 | CERTAIN SUBSTITUTED SPIROCYCLIC LACTAMS AND USE THEREOF AS PHARMACEUTICALS | NOVARTIS AG (CH) | 2005-04-21 | — | — | WO | disclosed |
| EP-1477186-A1 | ANTIPRURITICS | SHIONOGI & CO., LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6818640-B1 | BIND SELECTIVELY TO CANNABINOID 2 RECEPTOR; ANTIINFLAMMATORY AGENTS | SHIONOGI & CO., LTD. (JP) | 2004-11-16 | — | — | US | disclosed |
| CN-1514831-A | Medicinal composition containing 1,3-thiazine derivative | ��Ұ����ҩ��ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| US-20040116326-A1 | Medicinal composition containing 1,3-thiazine derivative | SHIONOGI & CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1375489-A1 | MEDICINAL COMPOSITION CONTAINING 1,3-THIAZINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
| CN-1387519-A | 2-imino-1, 3-thiazine derivatives | SHIONOGI & CO (JP) | 2002-12-25 | — | — | CN | disclosed |
| EP-1219612-A1 | 2-IMINO-1,3-THIAZINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-4792628-A | ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101590-A1 | Cannabinoid receptor agonists | CNR1, CNR2, OPRL1 | PNMT 410/4885ENPP2 187/4885LOXL2 1642/4885 |
| US-20240206470-A1 | VOLATILE APPLICATIONS AGAINST PATHOGENS | OXA1L, VAPB, TIAL1 | PNMT 3414/4885ENPP2 1635/4885LOXL2 114/4885 |
| US-12492163-B2 | 9H-fluorene derivatives or their pharmaceutically acceptable salts | BACE1, BACE2, APP | PNMT 476/4885ENPP2 2576/4885LOXL2 3924/4885 |
| US-20240068009-A1 | SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES | PGLS, AADAC, GLB1 | PNMT 2823/4885ENPP2 178/4885LOXL2 2523/4885 |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | PGLS, MRPL21, CLPP | PNMT 1477/4885ENPP2 1289/4885LOXL2 3586/4885 |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | PPARG, PPARA, PPARD | PNMT 3280/4885ENPP2 41/4885LOXL2 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.