Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91368 | 0.90 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL65367 | 0.88 | REN (0.38) | RENCYP3A4 | |
| SCHEMBL65792 | 0.87 | PPARA (0.39) | REN | |
| SCHEMBL65471 | 0.86 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL64056 | 0.84 | PPARG (0.38) | REN | |
| SCHEMBL78854 | 0.82 | PPARG (0.40) | REN | |
| SCHEMBL64503 | 0.82 | PPARA (0.33) | CYP3A4 | |
| SCHEMBL78866 | 0.80 | PPARG (0.36) | REN | |
| SCHEMBL91348 | 0.79 | REN (0.50) | RENCYP3A4 | |
| SCHEMBL64233 | 0.79 | CHRM5 (0.35) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |