Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 5/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64056 | 0.93 | PPARG (0.38) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL64503 | 0.93 | PPARA (0.33) | CHRM5CHRM1KDM4ELMNAITGB3 | |
| SCHEMBL78724 | 0.90 | KDM4E (0.34) | CHRM5CHRM1KDM4ELMNAITGB3 | |
| SCHEMBL65792 | 0.87 | PPARA (0.39) | CHRM5CHRM1KDM4ELMNAITGB3 | |
| SCHEMBL80037 | 0.86 | ITGB3 (0.32) | KDM4ELMNAITGB3ITGA2BPTGDR2 | |
| SCHEMBL65685 | 0.86 | CHRM5 (0.40) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL78781 | 0.84 | KDM4E (0.36) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL65231 | 0.83 | CHRM5 (0.39) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL78854 | 0.83 | PPARG (0.40) | KDM4ELMNAITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL64196 | 0.81 | GHSR (0.36) | CHRM5CHRM1KDM4ELMNAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |