Tyrosine

Tyrosine

SCHEMBL7701661

CC(C)C[C@H](N)C(=O)O.CCCC[C@H](N)C(=O)O.CCCC[C@H](NC=O)C(=O)OC(=O)[C@@H](N)CCCCN.N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 4/20 0.42
OPRM1 P35372 2/20 0.42
LNPEP Q9UIQ6 3/20 0.40
OPRK1 P41145 1/20 0.39
THRB P10828 1/20 0.39
NPY1R P25929 2/20 0.39
NPY4R P50391 2/20 0.39
NPY2R P49146 1/20 0.39
CTSK P43235 1/20 0.39
ERAP2 Q6P179 2/20 0.38
ERAP1 Q9NZ08 1/20 0.38
REN P00797 1/20 0.38
SLC7A5 Q01650 1/20 0.38
ANPEP P15144 1/20 0.38
NTSR2 O95665 1/20 0.37
NTSR1 P30989 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL7701663 0.92 OPRD1 (0.45) OPRD1OPRM1LNPEPOPRK1THRB
Tyrosine SCHEMBL6460601 0.85 SLC7A5 (0.50) OPRD1OPRM1LNPEPTHRBERAP2
Tyrosine SCHEMBL6460603 0.81 SLC7A5 (0.58) OPRD1OPRM1LNPEPTHRBERAP2
Tyrosine SCHEMBL4586603 0.80 SLC7A5 (0.60) LNPEPTHRBNPY1RNPY4RNPY2R
Tyrosine SCHEMBL1921852 0.78 SLC7A5 (0.55) LNPEPTHRBERAP2SLC7A5
SCHEMBL9197350 0.78 NPY4R (0.62) OPRD1OPRM1OPRK1NPY1RNPY4R
Dl-Phenylalanine SCHEMBL3691104 0.78 SLC7A5 (0.58) OPRK1THRBSLC7A5ANPEP
Phenylalanine SCHEMBL723829 0.78 SLC7A5 (0.58) OPRK1THRBSLC7A5ANPEP
SCHEMBL413804 0.77 NPY4R (0.56) OPRM1OPRK1NPY1RNPY4RNPY2R
SCHEMBL413803 0.77 NPY4R (0.56) OPRM1OPRK1NPY1RNPY4RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1267170-A1 Method for characterising polypeptides Xzillion GmbH & CO.KG (DE) 2002-12-18 EP disclosed