Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 6/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252426 | 1.00 | METAP2 (0.50) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL113611 | 0.96 | METAP2 (0.53) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL113612 | 0.96 | METAP2 (0.53) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL5443843 | 0.96 | METAP2 (0.53) | METAP2METAP1PPIDMARS1NOD1 | |
| Hydrochloric Acid SCHEMBL134493 | 0.94 | METAP2 (0.51) | METAP2METAP1PPIDMARS1NOD1 | |
| Hydrochloric Acid SCHEMBL8014832 | 0.94 | METAP2 (0.51) | METAP2METAP1PPIDMARS1NOD1 | |
| Hydrochloric Acid SCHEMBL2031642 | 0.94 | METAP2 (0.51) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL27499137 | 0.83 | MARS1 (0.40) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL1839255 | 0.82 | NOD1 (0.40) | METAP2METAP1NOD1CYP2D6CYP2C9 | |
| SCHEMBL1839254 | 0.82 | NOD1 (0.40) | METAP2METAP1NOD1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601970-A2 | DETECTION, MONITORING AND TREATMENT OF CANCER | THE OPEN UNIVERSITY (GB) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004081574-A2 | DETECTION, MONITORING AND TREATMENT OF CANCER | THE OPEN UNIVERSITY (GB) | 2004-09-23 | — | — | WO | disclosed |