Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.51 |
| ▸ | METAP1 | P53582 | 2/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 6/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2031642 | 1.00 | METAP2 (0.51) | METAP2METAP1PPIDMARS1NOD1 | |
| Hydrochloric Acid SCHEMBL8014832 | 1.00 | METAP2 (0.51) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL113611 | 0.98 | METAP2 (0.53) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL113612 | 0.98 | METAP2 (0.53) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL5443843 | 0.98 | METAP2 (0.53) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL6461273 | 0.94 | METAP2 (0.50) | METAP2METAP1PPIDMARS1NOD1 | |
| SCHEMBL1252426 | 0.94 | METAP2 (0.50) | METAP2METAP1PPIDMARS1NOD1 | |
| Hydrochloric Acid SCHEMBL27497759 | 0.85 | MARS1 (0.43) | METAP2METAP1MARS1NOD1RNPEP | |
| SCHEMBL1839254 | 0.84 | NOD1 (0.40) | METAP2METAP1NOD1ALOX15CYP2D6 | |
| SCHEMBL1839255 | 0.84 | NOD1 (0.40) | METAP2METAP1NOD1ALOX15CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115644297-A | Candy and preparation method thereof | 何桂霞 | 2023-01-31 | — | — | CN | claimed |
| CN-114344230-A | Composition for inhibiting bacteria, removing mites and removing acnes, and preparation method and application thereof | 广州美果生物科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-109234343-B | Methionine oligopeptide and preparation method and application thereof | 中国海洋大学 | 2020-12-01 | — | — | CN | claimed |
| US-20150045496-A1 | THERMO-REVERSIBLE POLYBUTADIENE RUBBER BLEND WITH SELF-HEALING NATURE | RELIANCE INDUSTRIES LIMITED (IN) | 2015-02-12 | — | — | US | claimed |
| WO-2013164843-A1 | THERMO-REVERSIBLE POLYBUTADIENE RUBBER BLEND WITH SELF-HEALING NATURE | RELIANCE INDUSTRIES LTD. (IN) | 2013-11-07 | — | — | WO | claimed |
| WO-2010117258-A1 | A METHOD OF SYNTHESISING AN AMINO ACID DERIVATIVE OF AZELAIC ACID | MALAYSIAN PALM OIL BOARD (MY) | 2010-10-14 | — | — | WO | claimed |
| US-6372788-B1 | — | — | None | — | — | US | disclosed |
| EP-4680222-A1 | N-BETA-HYDROXYBUTYRYL-AMINO ACIDS AND RELATED COMPOSITIONS AND METHODS | The Board of Trustees of the Leland Stanford Junior University (US) | 2026-01-21 | — | — | EP | disclosed |
| CN-119868228-A | Acne-removing composition capable of achieving targeted bacteriostasis and application thereof | 诺斯贝尔化妆品股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-12221445-B2 | Crystalline salts of 5-methyl-(6S)-tetrahydrofolic acid and amino ethyl esters | MERCK PATENT GMBH (DE) | 2025-02-11 | — | — | US | disclosed |
| US-12161620-B2 | Devices and methods for facilitating and controlling use of a medication | Jazz Pharmaceuticals, Inc. (US) | 2024-12-10 | — | — | US | disclosed |
| WO-2024192165-A1 | N-BETA-HYDROXYBUTYRYL-AMINO ACIDS AND RELATED COMPOSITIONS AND METHODS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-09-19 | — | — | WO | disclosed |
| EP-4425181-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | Bertis Inc (KR) | 2024-09-04 | — | — | EP | disclosed |
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |
| WO-1988006187-A1 | A PROCESS FOR ENZYMATIC PRODUCTION PRODUCTION OF DIPEPTIDES | CARLSBERG BIOTECHNOLOGY LTD. A/S (DK) | 1988-08-25 | — | — | WO | disclosed |
| EP-0278787-A1 | A process for enzymatic production of dipeptides | CARLBIOTECH LTD. A/S (DK) | 1988-08-17 | — | — | EP | disclosed |
| EP-0056565-B1 | DERIVATIVES OF DI(-2-CHLOROETHYL) AMINOPHENYL ALANINE WITH ANTITUMOUR ACTIVITY | PROTER S.p.A. (IT) | 1984-12-05 | — | — | EP | disclosed |
| US-4428875-A | TRIPEPTIDES INCLUDING METHIONINE | PROTER S.P.A. (IT) | 1984-01-31 | — | — | US | disclosed |
| EP-0056565-A1 | Derivatives of di(-2-chloroethyl) aminophenyl alanine with antitumour activity | PROTER S.p.A. (IT) | 1982-07-28 | — | — | EP | disclosed |
| US-4325954-A | ANTIDEPRESSANTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1982-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12161620-B2 | Devices and methods for facilitating and controlling use of a medication | CES2, OPRM1, UGT1A10 | METAP2 579/4885METAP1 750/4885PPID 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.