Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047185 | 0.90 | CTSL (0.37) | P2RX7CTSLALDH1A1EPHX2 | |
| SCHEMBL7567547 | 0.84 | ALDH1A1 (0.35) | MEN1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL6467927 | 0.81 | GAA (0.44) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6467203 | 0.78 | SMN1; SMN2 (0.35) | MEN1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL7049037 | 0.72 | KCNA5 (0.39) | ALDH1A1 | |
| SCHEMBL6475534 | 0.72 | SMN1; SMN2 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7049297 | 0.72 | HPGD (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7047980 | 0.72 | TBXA2R (0.37) | MEN1ALDH1A1KMT2ACNR1 | |
| SCHEMBL7046299 | 0.71 | L3MBTL1 (0.44) | ALDH1A1KMT2AEPHX2 | |
| SCHEMBL7044845 | 0.71 | KCNA5 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |