Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049297 | 0.89 | HPGD (0.40) | GAAHPGDLMNAALDH1A1NPSR1 | |
| SCHEMBL7567547 | 0.87 | ALDH1A1 (0.35) | HPGDLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL6461819 | 0.81 | P2RX7 (0.39) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL6467203 | 0.81 | SMN1; SMN2 (0.35) | HPGDLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL7049037 | 0.78 | KCNA5 (0.39) | GAALMNAALDH1A1MAPTPOLB | |
| SCHEMBL7047980 | 0.77 | TBXA2R (0.37) | LMNAALDH1A1NPSR1MAPTKMT2A | |
| SCHEMBL7046299 | 0.77 | L3MBTL1 (0.44) | HPGDLMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL7045334 | 0.77 | CYP1A2 (0.42) | ALDH1A1MAPTRAB9AKMT2APOLB | |
| SCHEMBL7044845 | 0.77 | KCNA5 (0.39) | HPGDLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7186575 | 0.76 | CACNA1H (0.37) | HPGDLMNAALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |