Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | POLA1 | P09884 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442662 | 1.00 | MEN1 (0.43) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL29442689 | 0.96 | KDM4E (0.48) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL1506593 | 0.96 | KDM4E (0.48) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL14609231 | 0.84 | MEN1 (0.43) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL17037970 | 0.79 | POLA1 (0.39) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL14925144 | 0.77 | ADCY6 (0.52) | ADCY6ADCY3ADCY9ADCY5ADCY8 | |
| SCHEMBL14925149 | 0.77 | ADCY6 (0.52) | ADCY6ADCY3ADCY9ADCY5ADCY8 | |
| SCHEMBL2819831 | 0.77 | HRH3 (0.43) | POLA1ACHE | |
| SCHEMBL10597541 | 0.76 | ERN1 (0.52) | ERN1TRIM24TRIM33 | |
| Bromide SCHEMBL14917356 | 0.76 | ADCY6 (0.50) | ADCY6ADCY3ADCY9ADCY5ADCY8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559504-B2 | Benzotriazole derivative | UBE CORPORATION (JP) | 2026-02-24 | — | — | US | disclosed |
| EP-3978073-B1 | 1H-BENZO[D][1,2,3]TRIAZOLE DERIVATIVES AS KEAP1 INHIBITORS FOR THE TREATMENT OF RENAL DISEASES | UBE CORP (JP) | 2025-10-15 | — | — | EP | disclosed |
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2022-08-18 | — | — | US | disclosed |
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2022-08-18 | — | — | US | disclosed |
| EP-3978073-A1 | BENZOTRIAZOLE DERIVATIVE | Ube Industries, Ltd. (JP) | 2022-04-06 | — | — | EP | disclosed |
| CN-114174289-A | Benzotriazole derivatives | 宇部兴产株式会社 | 2022-03-11 | — | — | CN | disclosed |
| WO-2020241853-A1 | BENZOTRIAZOLE DERIVATIVE | 宇部興産株式会社 | 2020-12-03 | — | — | WO | disclosed |
| US-9230827-B2 | Method for forming a resist under layer film and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-05 | — | — | US | disclosed |
| US-9230827-B2 | Method for forming a resist under layer film and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-05 | — | — | US | disclosed |
| US-9046764-B2 | Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-06-02 | — | — | US | disclosed |
| US-20080293776-A1 | 1,2,5-Thiazolidine Derivatives Useful for Treating Conditions Mediated by Protein Tyrosine Phosphatases (Ptpase) | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | disclosed |
| EP-1963294-A1 | 1,2,5-THIAZOLIDINE DERIVATIVES USEFUL FOR TREATING CONDITIONS MEDIATED BY PROTEIN TYROSINE PHOSPHATASES (PTPASE) | Novartis AG (CH) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067613-A1 | 1,2,5-THIAZOLIDINE DERIVATIVES USEFUL FOR TREATING CONDITIONS MEDIATED BY PROTEIN TYROSINE PHOSPHATASES (PTPASE) | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |
| CN-1150183-C | New heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | ɪά��ʵ���� | 2004-05-19 | — | — | CN | disclosed |
| EP-0768307-B1 | Heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-11-26 | — | — | EP | disclosed |
| US-5726208-A | Heterocyclic tertiary amines | ADIR ET COMPAGNIE (FR) | 1998-03-10 | — | — | US | disclosed |
| CN-1152572-A | New heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-06-25 | — | — | CN | disclosed |
| EP-0768307-A1 | Heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-04-16 | — | — | EP | disclosed |
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559504-B2 | Benzotriazole derivative | KEAP1, NFE2L2, NCOR1 | MEN1 3532/4885KMT2A 347/4885KDM4E 502/4885 |
| US-20080293776-A1 | 1,2,5-Thiazolidine Derivatives Useful for Treating Conditions Mediated by Protein Tyrosine Phosphatases (Ptpase) | PTPRS, PTPN5, PTPRR | MEN1 3927/4885KMT2A 2549/4885KDM4E 2554/4885 |
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | KEAP1, NFE2L2, BACH1 | MEN1 3589/4885KMT2A 111/4885KDM4E 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.