Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334501 | 0.78 | ALOX5 (0.69) | ACHETDP1MEN1KMT2AMAPK1 | |
| SCHEMBL490533 | 0.77 | NPC1 (0.52) | ACHEMEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL28121832 | 0.74 | GPR88 (0.52) | TDP1ALDH1A1HSD17B10CNR2GPR88 | |
| SCHEMBL28703363 | 0.73 | ATM (0.61) | ACHETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL28926942 | 0.72 | GPR88 (0.54) | MEN1KMT2AALDH1A1HSD17B10GPR88 | |
| SCHEMBL7040094 | 0.72 | TDP1 (0.59) | ACHETDP1MEN1KMT2AMAPK1 | |
| SCHEMBL4007061 | 0.71 | MEN1 (0.54) | TDP1MEN1KMT2AGPR88CA1 | |
| SCHEMBL10905939 | 0.71 | TDP1 (0.69) | ACHETDP1MEN1KMT2AMAPK1 | |
| SCHEMBL490908 | 0.70 | TDP1 (0.50) | TDP1MEN1KMT2AGPR88TSHR | |
| SCHEMBL432494 | 0.70 | NPC1 (0.52) | ACHEMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946537-B1 | PROCESS FOR THE STEREOSELECTIVE PRODUCTION OF NITRO-ENAMINE COMPOUNDS | ABBOTT LAB (US) | 2005-05-04 | — | — | EP | disclosed |