SCHEMBL6463101

SCHEMBL6463101

CC(C)S(=O)(=O)NC(=O)Nc1ccc(Cc2ccc(NC(=O)NS(=O)(=O)C(C)C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SAE1 Q9UBE0 3/20 0.51
UBA2 Q9UBT2 3/20 0.51
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA9 Q16790 4/20 0.46
CA12 O43570 3/20 0.46
TSHR P16473 1/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
CCNC P24863 1/20 0.43
CDK8 P49336 1/20 0.43
ATM Q13315 1/20 0.43
LMNA P02545 3/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8091346 0.82 ALDH1A1 (0.56) CA1CA2CA9CA12TSHR
SCHEMBL8083324 0.82 FPR2 (0.56) CA1CA2CA9CA12TSHR
SCHEMBL8626829 0.81 LMNA (0.56) SAE1UBA2CA1CA2CA9
SCHEMBL8663690 0.81 ACP1 (0.62) CA1CA2CA9CA12TSHR
SCHEMBL8091318 0.81 TP53 (0.56) CA1CA2CA9CA12KMT2A
SCHEMBL8083304 0.81 ALDH1A1 (0.54) CA1CA2CA9CA12TSHR
SCHEMBL8095025 0.81 FPR2 (0.55) CA1CA2CA9CA12TSHR
SCHEMBL6462904 0.80 HPGD (0.58) SAE1UBA2CA1CA2CA9
SCHEMBL2956788 0.75 SAE1 (0.53) SAE1UBA2CA1CA2CA9
SCHEMBL8083234 0.75 EPHX1 (0.62) CA1CA2CA9CA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed