SCHEMBL6463759

SCHEMBL6463759

Cc1ccc(S(=O)(=O)NC(=O)NCCC(=S)CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
LMNA P02545 3/20 0.68
TSHR P16473 2/20 0.68
ALB P02768 1/20 0.68
CYP2C9 P11712 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA9 Q16790 1/20 0.60
NPSR1 Q6W5P4 2/20 0.59
MAPT P10636 1/20 0.56
CYP3A4 P08684 1/20 0.54
THRB P10828 1/20 0.54
NFKB1 P19838 1/20 0.54
HTR2A P28223 1/20 0.54
CYP2C19 P33261 1/20 0.54
ADRA1A P35348 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
FBP1 P09467 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5931104 0.88 ALDH1A1 (0.79) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL19346235 0.87 ALDH1A1 (0.69) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL20335083 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL14273616 0.83 ALDH1A1 (0.83) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL8553271 0.83 ALDH1A1 (0.64) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL15145851 0.82 ALDH1A1 (0.71) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL6463765 0.81 ALDH1A1 (0.66) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL11537631 0.81 FBP1 (0.71) ALDH1A1LMNATSHRALBCYP2C9
Tolbutamide SCHEMBL15918 0.81 ALDH1A1 (1.00) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL6470242 0.81 FBP1 (0.71) ALDH1A1LMNATSHRALBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0535887-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US disclosed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US disclosed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP disclosed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP disclosed