SCHEMBL20335083

SCHEMBL20335083

COC(=O)CCNC(=O)NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.66
LMNA P02545 3/20 0.66
TSHR P16473 2/20 0.66
ALB P02768 1/20 0.66
CYP2C9 P11712 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
NPSR1 Q6W5P4 2/20 0.58
MAPT P10636 2/20 0.54
CYP3A4 P08684 1/20 0.52
THRB P10828 1/20 0.52
NFKB1 P19838 1/20 0.52
HTR2A P28223 1/20 0.52
CYP2C19 P33261 1/20 0.52
ADRA1A P35348 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
FBP1 P09467 7/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4929885 0.89 ALDH1A1 (0.67) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL4928600 0.89 ALDH1A1 (0.67) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL5931104 0.86 ALDH1A1 (0.79) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL19346235 0.85 ALDH1A1 (0.69) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL6463759 0.84 ALDH1A1 (0.68) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL6470242 0.82 FBP1 (0.71) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL14273616 0.82 ALDH1A1 (0.83) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL8575945 0.82 MAPT (0.63) ALDH1A1LMNAMAPT
SCHEMBL8553271 0.82 ALDH1A1 (0.64) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL15145851 0.81 ALDH1A1 (0.71) ALDH1A1LMNATSHRALBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 EP disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 ALDH1A1 1820/4885LMNA 2174/4885TSHR 2102/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 ALDH1A1 1666/4885LMNA 2562/4885TSHR 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.