SCHEMBL8553271

SCHEMBL8553271

Cc1ccc(S(=O)(=O)NC(=O)NCCC(F)=C(F)F)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
LMNA P02545 4/20 0.64
TSHR P16473 3/20 0.64
ALB P02768 1/20 0.64
CYP2C9 P11712 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
NPSR1 Q6W5P4 2/20 0.57
MAPT P10636 1/20 0.53
CYP3A4 P08684 1/20 0.51
THRB P10828 1/20 0.51
NFKB1 P19838 1/20 0.51
HTR2A P28223 1/20 0.51
CYP2C19 P33261 1/20 0.51
ADRA1A P35348 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5931104 0.85 ALDH1A1 (0.79) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL19346235 0.84 ALDH1A1 (0.69) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL6463759 0.83 ALDH1A1 (0.68) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL20335083 0.82 ALDH1A1 (0.66) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL14273616 0.81 ALDH1A1 (0.83) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL15145851 0.80 ALDH1A1 (0.71) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL11537631 0.78 FBP1 (0.71) ALDH1A1LMNATSHRALBCYP2C9
SCHEMBL6470242 0.78 FBP1 (0.71) ALDH1A1LMNATSHRALBCYP2C9
Tolbutamide SCHEMBL15918 0.78 ALDH1A1 (1.00) ALDH1A1LMNATSHRALBCYP2C9
Tolbutamide SCHEMBL1536920 0.78 ALDH1A1 (1.00) ALDH1A1LMNATSHRALBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1269136-A Fluoric alkenyl compound and use as insect repellent agent MONSANTO CO (US) 2000-10-11 CN disclosed
EP-0640069-B1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO CO (US) 1998-11-04 EP disclosed
EP-0798285-A2 3,4,4-Trifluoro-3-butenoic acid or its methyl ester MONSANTO COMPANY (US) 1997-10-01 EP disclosed
US-5623084-A INSECTICIDES, MITICIDES MONSANTO COMPANY (US) 1997-04-22 US disclosed
US-5561162-A SYSTEMIC PESTICIDES; NEMATOCIDES; INSECTICIDES; MITICIDES; EFFICIENCY; CROPS MONSANTO COMPANY (US) 1996-10-01 US disclosed
US-5457134-A Controlling nematodes, insects, acarids on plants MONSANTO COMPANY (US) 1995-10-10 US disclosed
EP-0640069-A1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1995-03-01 EP disclosed
US-5389680-A Insecticides, nematocides, miticides MONSANTO COMPANY (US) 1995-02-14 US disclosed
WO-1992015555-A2 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1992-09-17 WO disclosed