Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985986 | 0.95 | MLYCD (0.54) | FAAHCES1SIGMAR1MLYCDALOX5 | |
| SCHEMBL13181406 | 0.89 | MLYCD (0.64) | FAAHCES1MLYCD | |
| SCHEMBL8751616 | 0.82 | SIGMAR1 (0.61) | SIGMAR1ALOX5 | |
| SCHEMBL16658701 | 0.79 | SIGMAR1 (0.62) | SIGMAR1ALOX5FDPS | |
| SCHEMBL16658702 | 0.79 | SIGMAR1 (0.62) | SIGMAR1ALOX5FDPS | |
| SCHEMBL16658700 | 0.79 | SIGMAR1 (0.62) | SIGMAR1ALOX5FDPS | |
| SCHEMBL16658699 | 0.79 | SIGMAR1 (0.62) | SIGMAR1ALOX5FDPS | |
| SCHEMBL16658721 | 0.79 | SIGMAR1 (0.62) | SIGMAR1ALOX5FDPS | |
| SCHEMBL2316926 | 0.78 | RIPK1 (0.65) | MLYCD | |
| SCHEMBL15766120 | 0.78 | SIGMAR1 (0.61) | SIGMAR1ALOX5FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |