Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23676418 | 0.81 | CASP1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL6464360 | 0.80 | PTGER1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL2807342 | 0.80 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL8686960 | 0.77 | AGTR2 (0.56) | AGTR1AGTR2 | |
| SCHEMBL5147607 | 0.76 | CASP1 (0.54) | — | |
| SCHEMBL12496885 | 0.76 | RECQL (0.65) | SOAT1EPHX2POLB | |
| SCHEMBL8240985 | 0.76 | CASP1 (0.56) | — | |
| SCHEMBL5592400 | 0.76 | SOAT1 (0.48) | SOAT1POLB | |
| SCHEMBL3632239 | 0.76 | CA12 (0.62) | — | |
| Stearylsulfamide SCHEMBL9219328 | 0.75 | EPHX2 (0.57) | SOAT1EPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512681-A | HORMONE INHIBITORS FOR TREATMENT OF HYPERTENSION OR CONGESTIVE HEART FAILURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | claimed |
| US-5512681-A | HORMONE INHIBITORS FOR TREATMENT OF HYPERTENSION OR CONGESTIVE HEART FAILURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |